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TOP3B 抗体 (AA 128-824) (PE)

This 兔 多克隆 antibody specifically detects TOP3B in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8047586
发货至: 中国
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Quick Overview for TOP3B 抗体 (AA 128-824) (PE) (ABIN8047586)

抗原

See all TOP3B 抗体
TOP3B (Topoisomerase (DNA) III beta (TOP3B))

适用

  • 41
  • 32
  • 14
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 38
  • 4

克隆类型

  • 38
  • 4
多克隆

标记

  • 21
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TOP3B antibody is conjugated to PE

应用范围

  • 28
  • 18
  • 9
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 128-824

    原理

    Anti-TOP3B Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TOP3B recombinant protein (Position: E128-R824).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TOP3B (Topoisomerase (DNA) III beta (TOP3B))

    别名

    TOP3B

    背景

    Background: DNA topoisomerase 3-beta-1 is an enzyme that in humans is encoded by the TOP3B gene. This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

    Gene Full Name: DNA topoisomerase III beta

    基因ID

    8940

    UniProt

    O95985
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