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TLR7 抗体 (C-Term) (Fluoro550)

This 兔 多克隆 antibody specifically detects TLR7 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8047427
发货至: 中国
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Quick Overview for TLR7 抗体 (C-Term) (Fluoro550) (ABIN8047427)

抗原

See all TLR7 抗体
TLR7 (Toll-Like Receptor 7 (TLR7))

适用

  • 119
  • 61
  • 29
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 115
  • 18

克隆类型

  • 96
  • 36
  • 1
多克隆

标记

  • 60
  • 10
  • 10
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This TLR7 antibody is conjugated to Fluoro550

应用范围

  • 70
  • 48
  • 42
  • 33
  • 13
  • 9
  • 6
  • 4
  • 3
  • 3
Flow Cytometry (FACS)
  • 抗原表位

    • 29
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Toll-like receptor 7 TLR7 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat,mouse sequences by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human TLR7, different from the related rat and mouse sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TLR7 (Toll-Like Receptor 7 (TLR7))

    别名

    TLR7

    背景

    Background: TLR7 (Toll-like receptor 7) is protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. TLR7 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on human chromosome X. TLR7 recognises single stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages.

    Gene Full Name: toll like receptor 7

    Sequence Similarities: Belongs to the Toll-like receptor family.

    基因ID

    51284

    UniProt

    Q9NYK1

    途径

    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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