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TLR4 抗体 (N-Term) (APC)

This 兔 多克隆 antibody specifically detects TLR4 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN8047376
发货至: 中国
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Quick Overview for TLR4 抗体 (N-Term) (APC) (ABIN8047376)

抗原

See all TLR4 抗体
TLR4 (Toll-Like Receptor 4 (TLR4))

适用

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宿主

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克隆类型

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多克隆

标记

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This TLR4 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    N-Term

    原理

    Anti-Toll-like receptor 4 TLR4 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human TLR4.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TLR4 (Toll-Like Receptor 4 (TLR4))

    别名

    TLR4

    背景

    Background: TLR4, Toll-like receptor 4, is a protein that in humans is encoded by the TLR4 gene. TLR 4 is a toll-like receptor. TLR4, the human homolog of Drosophila Toll, is a type I transmembrane protein with an extracellular domain consisting of a leucine-rich repeat region and an intracellular domain homologous to that of human interleukin-1 receptor. The TLR4 gene is mapped to chromosome 9q32-q33 by fluorescence in situ hybridization.It detects lipopolysaccharide from Gram-negative bacteria and is thus important in the activation of the innate immune system.The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.

    Gene Full Name: toll like receptor 4

    Sequence Similarities: Belongs to the Toll-like receptor family.

    基因ID

    7099

    UniProt

    O00206

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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