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TLR10 抗体 (N-Term) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-TLR10 antibody (ABIN8047303) specifically detects TLR10 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN8047303
发货至: 中国
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Quick Overview for TLR10 抗体 (N-Term) (Biotin) (ABIN8047303)

抗原

See all TLR10 抗体
TLR10 (Toll-Like Receptor 10 (TLR10))

适用

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宿主

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克隆类型

  • 33
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多克隆

标记

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This TLR10 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    N-Term

    原理

    Anti-Toll-like receptor 10 TLR10 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human TLR10.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    TLR10 (Toll-Like Receptor 10 (TLR10))

    别名

    TLR10

    背景

    Background: TLR10 (Toll-like receptor 10), is a protein that in humans is encoded by the TLR10 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. By genomic sequence analysis, Hasan et al. (2005) determined that the TLR10 gene is clustered with TLR1 and TLR6 on chromosome 4p14. By coimmunoprecipitation analysis, Hasan et al. (2005) found that TLR10 associated with itself and with TLR1 and TLR2, but not with MD2. Signaling studies showed that TLR10 required MYD88, but not TIRAP, TRAM (TICAM2), or TRIF (TICAM1), to activate immune system promoters. Pro674 within the TLR10 TIR domain was required to activate all promoter examined.

    Gene Full Name: toll like receptor 10

    Sequence Similarities: Belongs to the Toll-like receptor family.

    基因ID

    81793

    UniProt

    Q9BXR5

    途径

    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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