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TOLLIP 抗体 (C-Term) (Fluoro550)

The 兔 多克隆 anti-TOLLIP antibody is suitable to detect TOLLIP in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8047251
发货至: 中国
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Quick Overview for TOLLIP 抗体 (C-Term) (Fluoro550) (ABIN8047251)

抗原

See all TOLLIP 抗体
TOLLIP (Toll Interacting Protein (TOLLIP))

适用

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人, 小鼠, 大鼠

宿主

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  • 12
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克隆类型

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多克隆

标记

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This TOLLIP antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-Toll-interacting protein Tollip Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Tollip.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TOLLIP (Toll Interacting Protein (TOLLIP))

    别名

    TOLLIP

    背景

    Background: TOLLIP (TOLL-Interacting Protein), is an inhibitory adaptor protein that in humans is encoded by the TOLLIP gene. Lo et al. (2009) stated that the TOLLIP gene maps to chromosome 11. The mouse gene maps to chromosome 7. By Western blot analysis of embryonic kidney cells, Burns et al. (2000) confirmed the binding of TOLLIP to IL1RAP, to a complex of IL1RAP-IL1R1, and to IL18R. Burns et al. (2000) proposed that IL1B stimulation induces aggregation of IL1Rs, recruitment of MYD88 followed by TOLLIP-IRAK complexes, and the phosphorylation of IRAK by MYD88. This leads to the dissociation of TOLLIP from IRAK, which can then transmit the IL1-induced signals.

    Gene Full Name: toll interacting protein

    Sequence Similarities: Belongs to the tollip family.

    基因ID

    54472

    UniProt

    Q9H0E2
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