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RRM2B 抗体 (AA 131-230) (FITC)

This anti-RRM2B antibody is a 兔 多克隆 antibody detecting RRM2B in WB, IF (cc) 和 IF (p). Suitable for 大鼠.
产品编号 ABIN755030
发货至: 中国

Quick Overview for RRM2B 抗体 (AA 131-230) (FITC) (ABIN755030)

抗原

See all RRM2B 抗体
RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This RRM2B antibody is conjugated to FITC

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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    AA 131-230

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human p53R2/RRM2B

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

    别名

    p53R2

    背景

    Synonyms: DKFZp686M05248, MGC102856, MGC42116, MTDPS8A, MTDPS8B, p53 inducible ribonucleotide reductase small subunit 2 homolog, p53 inducible ribonucleotide reductase small subunit 2 like protein, p53 R2, p53-inducible ribonucleotide reductase small subunit 2-like protein, p53R2, Ribonucleoside diphosphate reductase M2 subunit B, Ribonucleoside-diphosphate reductase subunit M2 B, Ribonucleotide reductase M2 B TP53 inducible, Ribonucleotide reductase M2 B, Ribonucleotide reductase small subunit like 2 p53 inducible, RIR2B_HUMAN, RRM 2B, RRM2B, TP53 inducible ribonucleotide reductase M2 B, TP53-inducible ribonucleotide reductase M2 B.

    Background: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010].

    基因ID

    50484

    途径

    p53 Pathway, Negative Regulation of intrinsic apoptotic Signaling
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