T-Bet 抗体 (Middle Region)
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北京 101111
Quick Overview for T-Bet 抗体 (Middle Region) (ABIN8045022)
抗原
See all T-Bet 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- Middle Region
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原理
- Anti-T-bet/Tbx21 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- identical to the related mouse,rat sequences.
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产品特性
- Anti-T-bet/Tbx21 Antibody-1. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human T-bet/Tbx21, identical to the related mouse and rat sequences.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Mouse Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- T-Bet
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别名
- TBX21
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背景
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Background: T-box transcription factor TBX21 is a protein that in humans is encoded by the TBX21 gene. It is mapped to 17q21.32. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Gene Full Name: T-box transcription factor 21
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分子量
- 65 kDa
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基因ID
- 30009
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UniProt
- Q9UL17
抗原
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