SYCP3 抗体 (AA 18-223) (Fluoro488)
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北京 101111
Quick Overview for SYCP3 抗体 (AA 18-223) (Fluoro488) (ABIN8044342)
抗原
See all SYCP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-223
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原理
- Anti-SCP3/SYCP3 Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human SCP3 shares 72%,73% amino acid (aa) sequences identity with mouse,rat SCP3,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SCP3 recombinant protein (Position: E18-E223). Human SCP3 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat SCP3, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))
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别名
- SYCP3
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背景
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Background: SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.
Gene Full Name: synaptonemal complex protein 3
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基因ID
- 50511
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UniProt
- Q8IZU3
抗原
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