SYNGAP1 抗体 (AA 3-1175) (Fluoro550)
Our Local Distributor
北京 101111
Quick Overview for SYNGAP1 抗体 (AA 3-1175) (Fluoro550) (ABIN8044255)
抗原
See all SYNGAP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 3-1175
-
原理
- Anti-SYNGAP1 Antibody Fluoro550 Conjugated
-
预测反应
- Human SYNGAP1 shares 99%,99.1% amino acid (aa) sequence identity with mouse,rat SYNGAP1,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SYNGAP1 recombinant protein (Position: R3-R1175). Human SYNGAP1 shares 99% and 99.1% amino acid (aa) sequence identity with mouse and rat SYNGAP1, respectively.
-
亚型
- IgG
-
-
anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (AA 1169-1183) antibody
Verified SYNGAP1 适用: 人, 小鼠 WB, ELISA, IF, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (AA 60-72) antibodyVerified SYNGAP1 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (C-Term) antibodySYNGAP1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (AA 1161-1343) antibodySYNGAP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) antibodySYNGAP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
-
别名
- SYNGAP1
-
背景
-
Background: Synaptic Ras GTPase-activating protein 1, also known as synaptic Ras-GAP 1 or SYNGAP1, is a protein that in humans is encoded by the SYNGAP1 gene. This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants.
Gene Full Name: synaptic Ras GTPase activating protein 1
-
基因ID
- 8831
-
UniProt
- Q96PV0
-
途径
- Regulation of long-term Neuronal Synaptic Plasticity
抗原
-
