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SYNGAP1 抗体

SYNGAP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7270663
发货至: 中国
  • 抗原 See all SYNGAP1 抗体
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    适用
    • 22
    • 16
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 21
    • 2
    克隆类型
    • 20
    • 3
    单克隆
    标记
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYNGAP1 antibody is un-conjugated
    应用范围
    • 11
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    SynGAP Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human SynGAP
    亚型
    IgG
    Top Product
    Discover our top product SYNGAP1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    别名
    SYNGAP1 (SYNGAP1 产品)
    别名
    SYNGAP1 antibody, Syngap antibody, MRD5 antibody, RASA1 antibody, RASA5 antibody, SYNGAP antibody, Gm1963 antibody, synaptic Ras GTPase activating protein 1 antibody, zinc finger and BTB domain containing 9 antibody, synaptic Ras GTPase activating protein 1 homolog (rat) antibody, SYNGAP1 antibody, ZBTB9 antibody, syngap1 antibody, Syngap1 antibody
    背景
    This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016],MRD5, RASA1, RASA5, SYNGAP,Cell Type Marker,Cell Type Marker_Neuron marker,Cell Type Marker_Synapse marker,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Neuroscience,Signal Transduction,SYNGAP1
    分子量
    147kDa
    基因ID
    8831
    UniProt
    Q96PV0
    途径
    Regulation of long-term Neuronal Synaptic Plasticity
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