Spt6 抗体 (AA 564-1639) (HRP)
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北京 101111
Quick Overview for Spt6 抗体 (AA 564-1639) (HRP) (ABIN8043817)
抗原
See all Spt6 (SUPT6H) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 564-1639
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原理
- Anti-Spt6/SUPT6H Antibody HRP Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Spt6/SUPT6H recombinant protein (Position: A564-Q1639).
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亚型
- IgG
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anti-Suppressor of Ty 6 Homolog (SUPT6H) (AA 425-475) antibody
SUPT6H 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 6 Homolog (SUPT6H) (AA 1500-1726) antibodySUPT6H 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 6 Homolog (SUPT6H) (AA 425-475) antibodySUPT6H 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 6 Homolog (SUPT6H) antibodySUPT6H 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 6 Homolog (SUPT6H) (N-Term) antibodySUPT6H 适用: 人, 犬, Cow, 马, 兔, 猴, 豚鼠, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 6 Homolog (SUPT6H) (AA 71-120) antibodySUPT6H 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 猴, 豚鼠, 小鸡, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 6 Homolog (SUPT6H) (AA 1050-1100) antibodySUPT6H 适用: 人, 小鼠 WB, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 6 Homolog (SUPT6H) (N-Term) antibodySUPT6H 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Spt6 (SUPT6H) (Suppressor of Ty 6 Homolog (SUPT6H))
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别名
- SUPT6H
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背景
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Background: Transcription elongation factor SPT6 is a protein that in humans is encoded by the SUPT6H gene. SUPT6H (suppressor of Ty6 homolog), also known as SPT6, SPT6H, Tat-CT2 (Tat-cotransactivator 2 protein) or emb-5 in C. elegans, is a 1,726 amino acid protein that is highly conserved from yeast to humans. Expressed ubiquitously, SUPT6H localizes to the nucleus and contains one SH2 domain and one S1 domain. SUPT6H participates in both DRB (5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole)-mediated transcriptional inhibition as well as the enhancement of transcriptional elongation by the RNA polymerase II (Pol II). SUPT6H interacts with the nuclear proteins SPT4 and SPT5, which comprise the DSIF (DRB-sensitivity-inducing factor) complex that binds RNA polymerase II, and ly regulates elongation. Via its C-terminus, SUPT6H can also interact with Histone H3. Due to alternative splicing events, three isoforms exist for SUPT6H. This antibody specifically recognizes the 230kd phosphorylated SUPT6H protein.
Gene Full Name: SPT6 homolog, histone chaperone and transcription elongation factor
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基因ID
- 6830
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UniProt
- Q7KZ85
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途径
- Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response
抗原
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