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SOCS1 抗体 (Middle Region) (Cy3)

The Cy3-conjugated 兔 多克隆 anti-SOCS1 antibody (ABIN8043724) specifically detects SOCS1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8043724
发货至: 中国
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Quick Overview for SOCS1 抗体 (Middle Region) (Cy3) (ABIN8043724)

抗原

See all SOCS1 抗体
SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

适用

  • 63
  • 47
  • 41
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
人, 小鼠, 大鼠

宿主

  • 61
  • 5
  • 2

克隆类型

  • 65
  • 3
多克隆

标记

  • 39
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SOCS1 antibody is conjugated to Cy3

应用范围

  • 45
  • 23
  • 21
  • 11
  • 10
  • 10
  • 9
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 11
    • 10
    • 9
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-SOCS1 Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human SOCS1, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

    别名

    SOCS1

    背景

    Background: Suppressor of cytokine signaling 1(SOCS1), also known as Jak-binding protein(JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.

    Gene Full Name: suppressor of cytokine signaling 1

    基因ID

    8651

    UniProt

    O15524

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, TLR signaling, Response to Growth Hormone Stimulus
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