SPHK1 抗体 (AA 16-267) (APC)
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北京 101111
Quick Overview for SPHK1 抗体 (AA 16-267) (APC) (ABIN8041703)
抗原
See all SPHK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 16-267
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原理
- Anti-SPHK1 Antibody APC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SPHK1 recombinant protein (Position: R16-H267).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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别名
- SPHK1
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背景
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Background: SPHK1(Sphingosine Kinase 1), is an enzyme that in humans is encoded by the SPHK1 gene. Melendez et al.(2000) mapped the SPHK1 gene to chromosome 17q25.2 based on sequence identity with ESTs mapped to this region. Kohama et al.(1998) demonstrated that recombinant mouse Sphk1 can specifically phosphorylate D-erythro-sphingosine and that D, L-threo-dihydrosphingosine and N, N-dimethylsphingosine can act as competitive inhibitors of recombinant Sphk1. Pitson et al.(2000) found that recombinant SPHK1 and endogenous SPHK1 purified from placenta had identical enzymatic characteristics, suggesting posttranslational modification does not effect functional properties.
Gene Full Name: sphingosine kinase 1
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基因ID
- 8877
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UniProt
- Q9NYA1
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途径
- VEGF Signaling
抗原
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