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Neurofibromin 1 抗体 (AA 2701-2839) (Biotin)

This anti-Neurofibromin 1 antibody (ABIN754425) is a Rabbit Polyclonal antibody detecting Neurofibromin 1 in ELISA, IHC (p), IHC (fro). Suitable for Human, Mouse.
产品编号 ABIN754425
发货至: 中国

Quick Overview for Neurofibromin 1 抗体 (AA 2701-2839) (Biotin) (ABIN754425)

抗原

See all Neurofibromin 1 (NF1) 抗体
Neurofibromin 1 (NF1)

适用

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人, 小鼠

宿主

  • 72
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克隆类型

  • 72
  • 8
多克隆

标记

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This Neurofibromin 1 antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 15
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    • 5
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    • 3
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    • 1
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    AA 2701-2839

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Neurofibromin 1

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Neurofibromin 1 (NF1)

    别名

    NF1

    背景

    Synonyms: Neurofibromin 1, DKFZp686J1293, FLJ21220, Neurofibromatosis Noonan syndrome, Neurofibromatosis related protein NF 1, Neurofibromatosis related protein NF1, neurofibromatosis type I, Neurofibromatosis-related protein NF-1, Neurofibromin 1, Neurofibromin truncated, Neurofibromin1, NF 1, NF, NF1, NF1_HUMAN, NFNS, Type 1 Neurofibromatosis, von Recklinghausen disease neurofibromin, von Recklinghausen disease related protein VRNF, VRNF, WATS, Watson disease related protein WSS, Watson syndrome, WSS.

    Background: This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].

    基因ID

    4763

    UniProt

    P21359

    途径

    cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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