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SMAD4 抗体 (C-Term) (Cy3)

The 兔 多克隆 anti-SMAD4 antibody is suitable to detect SMAD4 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8038038
发货至: 中国
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Quick Overview for SMAD4 抗体 (C-Term) (Cy3) (ABIN8038038)

抗原

See all SMAD4 抗体
SMAD4 (SMAD Family Member 4 (SMAD4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SMAD4 antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-Smad4 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Smad4, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SMAD4 (SMAD Family Member 4 (SMAD4))

    别名

    SMAD4

    背景

    Background: SMAD4 (Mothers Against Decapentaplegic Drosophila Homolog of 4), also known as MADH4 or DPC4, is a protein that in humans is encoded by the SMAD4 gene. It belongs to the Darfwin family of proteins that modulate members of the TGFβ protein superfamily. Hahn et al. (1996) identified the SMAD4 gene on chromosome 18q21.1. Howe et al. (1998) identified the SMAD4 gene within a region on 18q21.1 defined by linkage analysis in kindred with juvenile polyposis syndrome. To test ly the hypothesis that the SMAD4 gene is a tumor suppressor that is critical for transmitting signals from transforming growth factor-beta and related ligands. SMAD4 plays a pivotal role in signal transduction of the transforming growth factor beta superfamily cytokines by mediating transcriptional activation of target genes.

    Gene Full Name: SMAD family member 4

    Sequence Similarities: Belongs to the dwarfin/SMAD family.

    基因ID

    4089

    UniProt

    Q13485

    途径

    Cell Division Cycle, Chromatin Binding, Autophagy
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