LRP5 抗体 (AA 501-600)
Quick Overview for LRP5 抗体 (AA 501-600) (ABIN754078)
抗原
See all LRP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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特异性
- This antibody will recognize LRP6 due to high sequence similarity.
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LRP5
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亚型
- IgG
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anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 1000-1250) antibody
LRP5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (Internal Region) antibodyVerified LRP5 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibodyLRP5 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 451-550) antibodyLRP5 适用: 人, 小鼠, 大鼠 ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 769-1016) antibodyLRP5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 41-130) antibodyLRP5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 1538-1567) antibodyLRP5 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibodyLRP5 适用: 人 WB, FACS, EIA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 102-336) antibodyLRP5 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 41-130) antibodyLRP5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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别名
- LRP5
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背景
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Synonyms: HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, LRP-5, OPTA1, VBCH2, Low-density lipoprotein receptor-related protein 5, LRP5
Background: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.
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基因ID
- 4041
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UniProt
- O75197
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途径
- WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
抗原
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