SH2D1A 抗体 (Middle Region)
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北京 101111
Quick Overview for SH2D1A 抗体 (Middle Region) (ABIN8036866)
抗原
See all SH2D1A 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- Middle Region
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原理
- Anti-SH2D1A Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-SH2D1A Antibody. Tested in WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human SH2D1A.
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亚型
- IgG
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anti-SH2 Domain Containing 1A (SH2D1A) (AA 1-128) antibody
SH2D1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 1-128) antibodySH2D1A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 85-114), (C-Term) antibodySH2D1A 适用: 人 WB 宿主: 兔 Polyclonal RB41923 unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 11-124) antibodySH2D1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (C-Term) antibodySH2D1A 适用: 人, 兔, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 1-128) antibodySH2D1A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (Internal Region) antibodyVerified SH2D1A 适用: 人 WB, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 18-115) antibodySH2D1A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
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别名
- SH2D1A
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背景
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Background: This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: SH2 domain containing 1A
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分子量
- 16 kDa
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基因ID
- 4068
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UniProt
- O60880
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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