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SH2D1A 抗体 (Middle Region) (Fluoro594)

The Fluoro594-conjugated 兔 多克隆 anti-SH2D1A antibody (ABIN8036860) specifically detects SH2D1A in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8036860
发货至: 中国
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Quick Overview for SH2D1A 抗体 (Middle Region) (Fluoro594) (ABIN8036860)

抗原

See all SH2D1A 抗体
SH2D1A (SH2 Domain Containing 1A (SH2D1A))

适用

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宿主

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克隆类型

  • 60
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多克隆

标记

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This SH2D1A antibody is conjugated to Fluoro594

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    Middle Region

    原理

    Anti-SH2D1A Antibody Fluoro594 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human SH2D1A.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SH2D1A (SH2 Domain Containing 1A (SH2D1A))

    别名

    SH2D1A

    背景

    Background: This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: SH2 domain containing 1A

    基因ID

    4068

    UniProt

    O60880

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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