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SHBG 抗体 (AA 30-210)

This 兔 多克隆 antibody specifically detects SHBG in WB. It exhibits reactivity toward 人.
产品编号 ABIN8036831
发货至: 中国
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Room 801-803
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Quick Overview for SHBG 抗体 (AA 30-210) (ABIN8036831)

抗原

See all SHBG 抗体
SHBG (Sex Hormone Binding Globulin (SHBG))

适用

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宿主

  • 91
  • 51

克隆类型

  • 92
  • 50
多克隆

标记

  • 65
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This SHBG antibody is un-conjugated

应用范围

  • 89
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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 16
    • 15
    • 11
    • 9
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    • 5
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    • 2
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    • 1
    • 1
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    • 1
    AA 30-210

    原理

    Anti-Sex Hormone Binding Globulin/SHBG Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human SHBG shares 72% amino acid (aa) sequence identity with both mouse,rat SHBG.

    产品特性

    Anti-Sex Hormone Binding Globulin/SHBG Antibody. Tested in WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SHBG recombinant protein (Position: L30-A210). Human SHBG shares 72% amino acid (aa) sequence identity with both mouse and rat SHBG.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SHBG (Sex Hormone Binding Globulin (SHBG))

    别名

    SHBG

    背景

    Background: Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to the sex hormones,androgen and estrogen. SHBG is produced mostly by the liver and is released into the bloodstream. Other sites that produce SHBG include the brain, uterus, testes, and placenta. SHBG has both enhancing and inhibiting hormonal influences. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin. High estrogen, andthyroxine cause it to increase. It has been found that the monosaccharides glucose and fructose reduced human SHBG production by hepatocytes, irrespective of the presence of insulin, by downregulation of hepatocyte nuclear factor-4A and replacement of HNF4A by COUP-TFI at a cis-element within the human SHBG promoter, coincident with repression of its transcriptional activity.

    Gene Full Name: sex hormone binding globulin

    Sequence Similarities: Contains 2 laminin G-like domains.

    分子量

    70 kDa

    基因ID

    6462

    UniProt

    P04278

    途径

    Hormone Transport
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