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SECISBP2 抗体 (AA 12-854)

The 兔 多克隆 anti-SECISBP2 antibody is suitable to detect SECISBP2 in samples from 人. It has been validated for WB, ELISA, IF 和 ICC.
产品编号 ABIN8035053
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SECISBP2 抗体 (AA 12-854) (ABIN8035053)

抗原

See all SECISBP2 抗体
SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This SECISBP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

质量等级

Carrier-free
  • 抗原表位

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    AA 12-854

    原理

    Anti-SECISBP2 Antibody

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

    产品特性

    Anti-SECISBP2 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SECISBP2 recombinant protein (Position: E12-L854). Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

    别名

    SECISBP2

    背景

    Background: SECIS-binding protein 2 (commonly referred to as SBP2) is a protein that in humans is encoded by the SECISBP2 gene. The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element, present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene.

    Gene Full Name: SECIS binding protein 2

    分子量

    105 kDa

    基因ID

    79048

    UniProt

    Q96T21
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