SECISBP2 抗体 (AA 12-854)
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北京 101111
Quick Overview for SECISBP2 抗体 (AA 12-854) (ABIN8035053)
抗原
See all SECISBP2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 12-854
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原理
- Anti-SECISBP2 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.
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产品特性
- Anti-SECISBP2 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SECISBP2 recombinant protein (Position: E12-L854). Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- SECISBP2 (SECIS Binding Protein 2 (SECISBP2))
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别名
- SECISBP2
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背景
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Background: SECIS-binding protein 2 (commonly referred to as SBP2) is a protein that in humans is encoded by the SECISBP2 gene. The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element, present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene.
Gene Full Name: SECIS binding protein 2
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分子量
- 105 kDa
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基因ID
- 79048
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UniProt
- Q96T21
抗原
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