SECISBP2 抗体 (AA 12-854) (Fluoro594)
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北京 101111
Quick Overview for SECISBP2 抗体 (AA 12-854) (Fluoro594) (ABIN8035047)
抗原
See all SECISBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-854
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原理
- Anti-SECISBP2 Antibody Fluoro594 Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SECISBP2 recombinant protein (Position: E12-L854). Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SECISBP2 (SECIS Binding Protein 2 (SECISBP2))
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别名
- SECISBP2
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背景
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Background: SECIS-binding protein 2 (commonly referred to as SBP2) is a protein that in humans is encoded by the SECISBP2 gene. The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element, present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene.
Gene Full Name: SECIS binding protein 2
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基因ID
- 79048
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UniProt
- Q96T21
抗原
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