SLFN11 抗体 (AA 114-794) (Cy3)
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北京 101111
Quick Overview for SLFN11 抗体 (AA 114-794) (Cy3) (ABIN8034736)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 114-794
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原理
- Anti-SLFN11 Antibody Cy3 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SLFN11 recombinant protein (Position: P114-D794).
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亚型
- IgG
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anti-Schlafen Family Member 11 (SLFN11) (AA 670-821) antibody
SLFN11 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Schlafen Family Member 11 (SLFN11) (AA 114-794) antibodySLFN11 适用: 人 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SLFN11 (Schlafen Family Member 11 (SLFN11))
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别名
- SLFN11
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背景
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Background: Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene. SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition. Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents. Evidence suggests that in the presence of DNA-targeted therapies, SLFN11 is recruited to stressed replication forks where it blocks replication leading to cell death. SLFN11 is being explored as a predictive biomarker for response to DNA-targeted therapies.
Gene Full Name: schlafen family member 11
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基因ID
- 91607
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UniProt
- Q7Z7L1
抗原
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