SLFN11 抗体 (AA 114-794) (Biotin)
Our Local Distributor
北京 101111
Quick Overview for SLFN11 抗体 (AA 114-794) (Biotin) (ABIN8034735)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 114-794
-
原理
- Anti-SLFN11 Antibody Biotin Conjugated
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SLFN11 recombinant protein (Position: P114-D794).
-
亚型
- IgG
-
-
anti-Schlafen Family Member 11 (SLFN11) (AA 670-821) antibody
SLFN11 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Schlafen Family Member 11 (SLFN11) (AA 114-794) antibodySLFN11 适用: 人 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- SLFN11 (Schlafen Family Member 11 (SLFN11))
-
别名
- SLFN11
-
背景
-
Background: Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene. SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition. Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents. Evidence suggests that in the presence of DNA-targeted therapies, SLFN11 is recruited to stressed replication forks where it blocks replication leading to cell death. SLFN11 is being explored as a predictive biomarker for response to DNA-targeted therapies.
Gene Full Name: schlafen family member 11
-
基因ID
- 91607
-
UniProt
- Q7Z7L1
抗原
-
