SKP2 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for SKP2 抗体 (C-Term) (ABIN8034238)
抗原
See all SKP2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- C-Term
-
原理
- Anti-SKP2 Antibody
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-SKP2 Antibody. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human SKP2, which shares 88.9% and 94.4% amino acid (aa) sequence identity with mouse and rat SKP2, respectively.
-
亚型
- IgG
-
-
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 351-424) antibody
SKP2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (C-Term) antibodySKP2 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-100) antibodySKP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 221-425) antibodySKP2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 43-397) antibodySKP2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-424) antibodySKP2 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 适用: 人 WB, IHC, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (N-Term) antibodySKP2 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-130) antibodySKP2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 6G9D10 unconjugated
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
-
别名
- SKP2
-
背景
-
Background: The F box protein Skp2 (S-phase kinase-associated protein 2) is oncogenic, and its frequent amplification and overexpression correlate with the grade of malignancy of certain tumors. Skp2 controls p300-p53 signaling pathways in cancer cells, making it a potential molecular target for cancer therapy. This gene positively regulates the G (1)-S transition by controlling the stability of several G (1) regulators, such as the cell cycle inhibitor p27. This study provides evidence of a role for an F-box protein in oncogenesis and establishes SKP2 as a protooncogene causally involved in the pathogenesis of lymphomas.
Gene Full Name: S-phase kinase associated protein 2
-
分子量
- 46, 48 kDa
-
基因ID
- 6502
-
UniProt
- Q13309
-
途径
- Mitotic G1-G1/S Phases
抗原
-
