SAG 抗体 (AA 193-405) (APC)
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Quick Overview for SAG 抗体 (AA 193-405) (APC) (ABIN8034213)
抗原
See all SAG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 193-405
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原理
- Anti-Retinal S antigen/SAG Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Retinal S antigen recombinant protein (Position: R193-E405).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))
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别名
- SAG
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背景
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Background: S-arrestin is a protein that in humans is encoded by the SAG gene. Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.
Gene Full Name: S-antigen visual arrestin
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基因ID
- 6295
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UniProt
- P10523
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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