SAG 抗体 (AA 210-290)
Our Local Distributor
北京 101111
Quick Overview for SAG 抗体 (AA 210-290) (ABIN7227368)
抗原
See all SAG 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 210-290
-
原理
- Rabbit Anti-ARRS Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of ARRS protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human ARRS protein at AA range: 210-290
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))
-
别名
- ARRS
-
背景
- S-arrestin, 48 kDa protein, Retinal S-antigen, Rod photoreceptor arrestinSAG (S-Antigen Visual Arrestin) is a Protein Coding gene. Diseases associated with SAG include Oguchi Disease-1 and Retinitis Pigmentosa 47. Among its related pathways are Phototransduction and Visual Cycle in Retinal Rods. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in SAG have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.
-
分子量
- 44kD
-
基因ID
- 6295
-
UniProt
- P10523
-
途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
-