BRIP1 抗体 (HRP)
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北京 101111
Quick Overview for BRIP1 抗体 (HRP) (ABIN753727)
抗原
See all BRIP1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 小鼠, 大鼠, 兔, 牛, 猪, 马, 犬, 小鸡
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纯化方法
- Antibodies are purified by protein A and peptide affinity chromatography.
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免疫原
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Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human BACH1
Please inquire for sequence information. -
亚型
- IgG
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应用备注
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WB(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1mg/1ml
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缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % Gentamicin.
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储存液
- Gentamicin sulfate
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储存条件
- -20 °C
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- BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))
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别名
- BACH1/BRIP1
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背景
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BACH1 is a member of the DEAH helicase family that interacts with BRCA1 in vivo. BACH1 is a DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. BACH1 acts late in the Fanconi anemia pathway after FANCD2 ubiquitination and is involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore it is likely that BACH1 is a target of germline cancer-inducing mutations.
Synonym: BACH 1, BRIP1, BACH-1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1, BRCA1 binding helicase like protein BACH1, BRCA1 interacting protein C terminal helicase 1, BRIP 1, BRIP-1, FANCJ, ATP dependent RNA helicase BRIP1, Fanconi anemia group J protein, FLJ90232, MGC126521, MGC126523, OF antibody Protein FACJ. -
分子量
- 130kDa
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基因ID
- 571
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途径
- DNA Damage Repair
抗原
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