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POLR2A/RPB1 抗体 (AA 10-321) (FITC)

The 兔 多克隆 anti-POLR2A/RPB1 antibody is suitable to detect POLR2A/RPB1 in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for FACS.
产品编号 ABIN8033835
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for POLR2A/RPB1 抗体 (AA 10-321) (FITC) (ABIN8033835)

抗原

See all POLR2A/RPB1 (POLR2A) 抗体
POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 116
  • 19
  • 1
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克隆类型

  • 72
  • 66
多克隆

标记

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This POLR2A/RPB1 antibody is conjugated to FITC

应用范围

  • 99
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  • 11
  • 10
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Flow Cytometry (FACS)
  • 抗原表位

    • 30
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    • 12
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    AA 10-321

    原理

    Anti-RNA polymerase II/POLR2A Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human RNA polymerase II/POLR2A recombinant protein (Position: D10-E321).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

    别名

    POLR2A

    背景

    Background: DNA-ed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that in humans is encoded by the POLR2A gene. It is mapped to 17p13.1. This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

    Gene Full Name: RNA polymerase II subunit A

    基因ID

    5430

    UniProt

    P24928

    途径

    Regulatory RNA Pathways
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