RMI2 抗体 (AA 23-147)
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北京 101111
Quick Overview for RMI2 抗体 (AA 23-147) (ABIN8033459)
抗原
See all RMI2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 23-147
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原理
- Anti-C16orf75/RMI2 Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human RMI2 shares 87.2% amino acid (aa) sequence identity with mouse RMI2.
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产品特性
- Anti-C16orf75/RMI2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human C16orf75/RMI2 recombinant protein (Position: L23-P147). Human RMI2 shares 87.2% amino acid (aa) sequence identity with mouse RMI2.
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亚型
- IgG
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anti-RMI2, RecQ Mediated Genome Instability 2 (RMI2) (C-Term) antibody
RMI2 适用: 人, 小鼠, 大鼠 WB, FACS, IHC, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RMI2, RecQ Mediated Genome Instability 2 (RMI2) (AA 1-147) antibodyRMI2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RMI2, RecQ Mediated Genome Instability 2 (RMI2) (AA 23-147) antibodyRMI2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- RMI2 (RMI2, RecQ Mediated Genome Instability 2 (RMI2))
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别名
- RMI2
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背景
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Background: RMI2 is a component of the BLM (RECQL3) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability. This gene is mapped to 16p13.13. RMI1 and RMI2 were present in approximately stoichiometric amounts with other BLM complex components, including topoisomerase-3-alpha (TOP3A), RPA (see RPA1), and BLAP250. RMI2 also associated with RMI1 and TOP3A in a second complex. RMI1 and RMI2 interacted ly, and both were essential for stability of the BLM complex. Depletion of either RMI1 or RMI2 depleted the other protein by 80 to 90 % . Chicken DT40 cells depleted of Rmi2 displayed elevated sister chromatid exchange, but other functions of the BLM complex appeared intact. Mutation analysis revealed that interaction between human RMI2 and BLM was essential for suppression of sister chromatid exchange.
Gene Full Name: RecQ mediated genome instability 2
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分子量
- 16 kDa
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基因ID
- 116028
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UniProt
- Q96E14
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途径
- DNA Damage Repair
抗原
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