RNF20 抗体 (AA 123-389) (Fluoro647)
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Quick Overview for RNF20 抗体 (AA 123-389) (Fluoro647) (ABIN8033260)
抗原
See all RNF20 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 123-389
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原理
- Anti-RNF20 Antibody (monoclonal, 3C6E2) Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RNF20 recombinant protein (Position: E123-S389).
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亚型
- IgG2b
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- RNF20 (Ring Finger Protein 20 (RNF20))
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别名
- RNF20
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背景
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Background: E3 ubiquitin-protein ligase BRE1A is an enzyme that in humans is encoded by the RNF20 gene. The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).
Gene Full Name: ring finger protein 20
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基因ID
- 56254
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UniProt
- Q5VTR2
抗原
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