RNF169 抗体 (AA 311-708) (PE)
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北京 101111
Quick Overview for RNF169 抗体 (AA 311-708) (PE) (ABIN8033215)
抗原
See all RNF169 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-708
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原理
- Anti-RNF169 Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RNF169 recombinant protein (Position: N311-K708).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- RNF169 (Ring Finger Protein 169 (RNF169))
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别名
- RNF169
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背景
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Background: RING finger protein 169 (RNF169) is a probable E3 ubiquitin-protein ligase that acts as a negative regulator of the repair of double-strand breaks (DSBs) following DNA damage. RNF169 is recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSB repair. This gene is mapped to 11q13.4.
Gene Full Name: ring finger protein 169
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基因ID
- 254225
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UniProt
- Q8NCN4
抗原
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