RNF111 抗体 (AA 134-994) (APC)
Our Local Distributor
北京 101111
Quick Overview for RNF111 抗体 (AA 134-994) (APC) (ABIN8033170)
抗原
See all RNF111 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 134-994
-
原理
- Anti-RNF111 Antibody APC Conjugated
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human RNF111 recombinant protein (Position: F134-S994).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- RNF111 (Ring Finger Protein 111 (RNF111))
-
别名
- RNF111
-
背景
-
Background: E3 ubiquitin-protein ligase Arkadia is an enzyme that in humans is encoded by the RNF111 gene. The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Gene Full Name: ring finger protein 111
-
基因ID
- 54778
-
UniProt
- Q6ZNA4
抗原
-