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HMGCR 抗体 (pSer872)

Name: HMGCR 抗体 (pSer872)
SKU: ABIN753283
Availability: OutOfStock

This anti-HMGCR antibody is a 兔多克隆 antibody detecting HMGCR in WB, ELISA, FACS, IF (cc), IF (p), IHC (fro) 和 IHC (p). Suitable for 人, 大鼠和小鼠. This Primary Antibody has been cited in 2+ publications.

Formalin-fixed and paraffin embedded rat liver tissue labeled with Anti-phospho-HMGCR(Ser872) Polyclonal Antibody, Unconjugated (ABIN753283) at 1:200 followed by conjugation to the secondary antibody and DAB staining (HMGCR 抗体 (pSer872))

IHC

Formalin-fixed and paraffin embedded mouse brain labeled with Rabbit Anti-HMGCR(Ser872) Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (HMGCR 抗体 (pSer872))

IHC (p)

Formalin-fixed and paraffin embedded mouse intestine labeled with Rabbit Anti-HMGCR(Ser872) Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (HMGCR 抗体 (pSer872))

IHC (p)

3 images

(2 references)

产品编号 ABIN753283

发货至: 中国

Quick Overview for HMGCR 抗体 (pSer872) (ABIN753283)

抗原

See all HMGCR 抗体

HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

适用

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

This HMGCR antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product HMGCR Primary Antibody

抗原表位
16

15

6

3

1

1

1

1

1

1

1

1
pSer872

特异性

This phosphorylation site is homologous to that of Ser871 in Mouse and Rat.

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Cow,Pig,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human HMGCR around the phosphorylation site of Ser872

亚型

IgG
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 629-888) antibody
HMGCR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 638-887) antibody
HMGCR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 588-887) antibody
HMGCR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (N-Term) antibody
HMGCR 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 251-350) antibody
HMGCR 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (Internal Region) antibody
Verified HMGCR 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated

anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-835) antibody
HMGCR 适用: 人 IP 宿主: 兔 Polyclonal unconjugated

anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) antibody
HMGCR 适用: 人, 大鼠, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (pSer872) antibody (Biotin)
HMGCR 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal Biotin

anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (pSer872) antibody (AbBy Fluor® 750)
HMGCR 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 750

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Zanoni, Aiello, Arnoldi, Lammi: "Hempseed Peptides Exert Hypocholesterolemic Effects with a Statin-Like Mechanism." in: Journal of agricultural and food chemistry, Vol. 65, Issue 40, pp. 8829-8838, (2017) (PubMed).

Yang, Ouyang, Chen, Pang, Dong, Yang, Liu, Peng, Wang, Zhang, Ren: "HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death." in: The Journal of general virology, Vol. 95, Issue Pt 6, pp. 1330-7, (2014) (PubMed).
抗原

HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

别名

HMGCR

背景

Synonyms: LDLCQ3, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase, HMGCR, phospho HMGCR, p-HMGCR
Background: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

基因ID

3156

UniProt

P04035

途径

AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha