PRKAG3 抗体 (C-Term)
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北京 101111
Quick Overview for PRKAG3 抗体 (C-Term) (ABIN8027653)
抗原
See all PRKAG3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-PRKAG3 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-PRKAG3 Antibody. Tested in WB applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PRKAG3.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
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别名
- PRKAG3
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背景
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Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Gene Full Name: protein kinase AMP-activated non-catalytic subunit gamma 3
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分子量
- 54 kDa
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基因ID
- 53632
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UniProt
- Q9UGI9
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途径
- AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effect
抗原
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