PKC gamma 抗体 (C-Term)
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Quick Overview for PKC gamma 抗体 (C-Term) (ABIN8027530)
抗原
See all PKC gamma (PRKCG) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-PKC gamma/PRKCG Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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产品特性
- Anti-PKC gamma/PRKCG Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PKC gamma, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Protein Kinase C, gamma (PRKCG) (pThr514) antibody
KD Validated PRKCG 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4490 unconjugated Recombinant Antibody
anti-Protein Kinase C, gamma (PRKCG) (pThr514) antibodyPRKCG 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 260-351) antibodyPRKCG 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (Internal Region) antibodyPRKCG 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) antibodyPRKCG 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4495 unconjugated Recombinant Antibody
anti-Protein Kinase C, gamma (PRKCG) (AA 305-336), (C-Term) antibodyPRKCG 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1007 unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 87-338) antibodyPRKCG 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1G5B3 unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 1-314) antibodyPRKCG 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (Thr655) antibodyPRKCG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 539-588) antibodyPRKCG 适用: 人, 大鼠, 小鼠, Cow, 兔, 猴, 犬, 豚鼠, 马, 斑马鱼, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Rat, Human, Mouse
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
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别名
- PRKCG
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背景
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Background: The gamma isotype of protein kinase C (PKC gamma) is a member of the classical PKC (cPKC) subfamily which is activated by Ca (2+) and diacylglycerol in the presence of phosphatidylserine. Physiologically, PKC gamma is activated by a mechanism coupled with receptor-mediated breakdown of inositol phospholipid as other cPKC isotypes such as PKC alpha and PKC beta. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons, while PKC alpha and PKC beta are expressed in many tissues in addition to the brain. Within the brain, PKC gamma is the most abundant in the cerebellum, hippocampus and cerebral cortex, where the existence of neuronal plasticity has been demonstrated. PKC gamma gene is mutated in spinocerebellar ataxia type 14 (SCA14). Verbeek et al. (2005) point out the specific alterations in mutant PKC gamma function that could lead to the selective neuronal degeneration of SCA14.
Gene Full Name: protein kinase C gamma
Sequence Similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
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分子量
- 104 kDa
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基因ID
- 5582
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UniProt
- P05129
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途径
- WNT signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
抗原
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