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PKC beta 抗体 (AA 542-671) (PE)

The PE-conjugated 兔 多克隆 anti-PKC beta antibody (ABIN8027440) specifically detects PKC beta in FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8027440
发货至: 中国
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Quick Overview for PKC beta 抗体 (AA 542-671) (PE) (ABIN8027440)

抗原

See all PKC beta (PRKCB) 抗体
PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PKC beta antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 542-671

    原理

    Anti-PKC beta 1/PRKCB Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human PKC beta 1 shares 100% amino acid (aa) sequence identity with both mouse,rat PKC beta 1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PKC beta 1 recombinant protein (Position: E542-V671). Human PKC beta 1 shares 100% amino acid (aa) sequence identity with both mouse and rat PKC beta 1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

    别名

    PRKCB

    背景

    Background: Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. It is a member of the protein kinase C (PKC) gene family. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. It has been found that PRKCB activated by oxidative conditions in the cell, induces phosphorylation of p66 (SHC) and triggers mitochondrial accumulation of the protein after it is recognized by the prolyl isomerase PIN1.

    Gene Full Name: protein kinase C beta

    Sequence Similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

    基因ID

    5579

    UniProt

    P05771

    途径

    WNT signaling, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling
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