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POMC 抗体 (Middle Region) (PE)

The PE-conjugated 兔 多克隆 anti-POMC antibody (ABIN8026123) specifically detects POMC in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8026123
发货至: 中国
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Quick Overview for POMC 抗体 (Middle Region) (PE) (ABIN8026123)

抗原

See all POMC 抗体
POMC (Proopiomelanocortin (POMC))

适用

  • 84
  • 64
  • 64
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 73
  • 32
  • 1

克隆类型

  • 62
  • 44
多克隆

标记

  • 60
  • 7
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This POMC antibody is conjugated to PE

应用范围

  • 47
  • 41
  • 36
  • 33
  • 19
  • 17
  • 13
  • 13
  • 11
  • 9
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 11
    • 10
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-ACTH/POMC Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human ACTH, different from the related mouse and rat sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    POMC (Proopiomelanocortin (POMC))

    别名

    POMC

    背景

    Background: Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. ACTH stimulates secretion of glucocorticoid steroid hormones from adrenal cortex cells, especially in the zona fasciculata of the adrenal glands. This gene can influence steroid hormone secretion by both rapid short-term mechanisms that take place within minutes and slower long-term actions. Besides, ACTH also enhances transcription of mitochondrial genes that encode for subunits of mitochondrial oxidative phosphorylation systems.

    Gene Full Name: proopiomelanocortin

    Sequence Similarities: Belongs to the POMC family.

    基因ID

    5443

    UniProt

    P01189

    途径

    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
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