Prohibitin 抗体 (C-Term)
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Quick Overview for Prohibitin 抗体 (C-Term) (ABIN8025661)
抗原
See all Prohibitin (PHB) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-Prohibitin/PHB Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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产品特性
- Anti-Prohibitin/PHB Antibody. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Prohibitin, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Prohibitin (PHB) (AA 1-272) antibody
PHB 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F4-2B2 unconjugated
anti-Prohibitin (PHB) antibodyPHB 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H7 unconjugated
anti-Prohibitin (PHB) antibodyKO Validated PHB 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 177-272) antibodyPHB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal PHB-3194 unconjugated
anti-Prohibitin (PHB) (AA 73-272) antibodyPHB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal PHB-3231 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal PHB-3230 unconjugated
anti-Prohibitin (PHB) (AA 89-117) antibodyPHB 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB17513 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal PHB-1881 unconjugated
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应用备注
- Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human, Mouse, RatImmunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, MouseWestern blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Prohibitin (PHB)
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别名
- PHB
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背景
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Background: PHB (Prohibitin), also known as PHB1, is a protein that in humans is encoded by the PHB gene. White et al. (1991) mapped the PHB gene to chromosome 17 by analysis of human-mouse somatic cell hybrid cell lines using a genomic fragment of human prohibitin DNA isolated from a library using the rat prohibitin cDNA clone. By in situ hybridization, they localized the gene to 17q21. Sato et al. (1992) isolated the human homolog of the rat prohibitin gene and mapped it to 17q12-q21 by in situ hybridization. Proliferation of tumor cells depends on new blood vessel formation (angiogenesis) that accompanies malignant progression. Anticancer therapies using angiogenesis inhibitors or cytotoxic agents targeted to the vasculature of tumors have been evaluated in clinical trials. Although white fat is a nonmalignant tissue, it has the capability to quickly proliferate and expand. Furthermore, it is highly vascularized. Rupnick et al. (2002) showed that nonspecific angiogenesis inhibitors can prevent the development of obesity of mice.
Gene Full Name: prohibitin 1
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分子量
- 30 kDa
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基因ID
- 5245
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UniProt
- P35232
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
-
