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ALIX 抗体 (AA 2-330) (APC)

The APC-conjugated 兔 多克隆 anti-ALIX antibody (ABIN8025625) specifically detects ALIX in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8025625
发货至: 中国
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Quick Overview for ALIX 抗体 (AA 2-330) (APC) (ABIN8025625)

抗原

See all ALIX (PDCD6IP) 抗体
ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

适用

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人, 小鼠, 大鼠

宿主

  • 88
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克隆类型

  • 70
  • 44
多克隆

标记

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This ALIX antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 23
    • 15
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    AA 2-330

    原理

    Anti-ALIX/PDCD6IP Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human ALIX shares 96.7%,95.2% amino acid (aa) sequence identity with mouse,rat ALIX,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ALIX recombinant protein (Position: A2-D330). Human ALIX shares 96.7% and 95.2% amino acid (aa) sequence identity with mouse and rat ALIX, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

    别名

    PDCD6IP

    背景

    Background: Programmed cell death 6-interacting protein is a protein that in humans is encoded by the PDCD6IP gene. This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: programmed cell death 6 interacting protein

    基因ID

    10015

    UniProt

    Q8WUM4

    途径

    p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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