PGRMC1 抗体 (Middle Region) (HRP)
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北京 101111
Quick Overview for PGRMC1 抗体 (Middle Region) (HRP) (ABIN8025479)
抗原
See all PGRMC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-PGRMC1 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- identical to the related mouse sequence,and different from the related rat sequence by two amino acids.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PGRMC1, identical to the related mouse sequence, and different from the related rat sequence by two amino acids.
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亚型
- IgG
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anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (C-Term) antibody
Verified PGRMC1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 1-195) antibodyPGRMC1 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G11G8 unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 44-195) antibodyPGRMC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (Middle Region) antibodyPGRMC1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 96-195) antibodyPGRMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (C-Term) antibodyPGRMC1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 145-195) antibodyPGRMC1 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibodyPGRMC1 适用: 人, Cow, 犬, 马, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibodyPGRMC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))
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别名
- PGRMC1
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背景
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Background: Progesterone receptor membrane component 1 (PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene. The Sigma-2 receptor was recently identified as potentially being the same as PGRMC1. The sole biochemical function of PGRMC1 is heme-binding. PGRMC1 shares key structural motifs with cytochrome b5. It binds and activates P450 proteins, which are important in drug, hormone and lipid metabolism. Also, PGRMC1 binds to PAIR-BP1 (plasminogen activator inhibitor RNA-binding protein-1). However, its expression outside of the reproductive tract and in males suggests multiple functions for the protein. These may include binding to Insig (insulin-induced gene), which regulates cholesterol synthesis.
Gene Full Name: progesterone receptor membrane component 1
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基因ID
- 10857
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UniProt
- O00264
抗原
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