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PGRMC1 抗体 (Middle Region) (Fluoro550)

This 兔 多克隆 antibody specifically detects PGRMC1 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8025476
发货至: 中国
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Quick Overview for PGRMC1 抗体 (Middle Region) (Fluoro550) (ABIN8025476)

抗原

See all PGRMC1 抗体
PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))

适用

  • 36
  • 27
  • 25
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 33
  • 2
  • 1

克隆类型

  • 34
  • 2
多克隆

标记

  • 20
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PGRMC1 antibody is conjugated to Fluoro550

应用范围

  • 20
  • 16
  • 12
  • 9
  • 6
  • 3
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 11
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-PGRMC1 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse sequence,and different from the related rat sequence by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human PGRMC1, identical to the related mouse sequence, and different from the related rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))

    别名

    PGRMC1

    背景

    Background: Progesterone receptor membrane component 1 (PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene. The Sigma-2 receptor was recently identified as potentially being the same as PGRMC1. The sole biochemical function of PGRMC1 is heme-binding. PGRMC1 shares key structural motifs with cytochrome b5. It binds and activates P450 proteins, which are important in drug, hormone and lipid metabolism. Also, PGRMC1 binds to PAIR-BP1 (plasminogen activator inhibitor RNA-binding protein-1). However, its expression outside of the reproductive tract and in males suggests multiple functions for the protein. These may include binding to Insig (insulin-induced gene), which regulates cholesterol synthesis.

    Gene Full Name: progesterone receptor membrane component 1

    基因ID

    10857

    UniProt

    O00264
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