PNKP 抗体 (AA 43-487)
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北京 101111
Quick Overview for PNKP 抗体 (AA 43-487) (ABIN8024396)
抗原
See all PNKP 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 43-487
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原理
- Anti-PNKP Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.
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产品特性
- Anti-PNKP Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PNKP recombinant protein (Position: D43-E487). Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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别名
- PNKP
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背景
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Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Gene Full Name: polynucleotide kinase 3'-phosphatase
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分子量
- 57 kDa
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基因ID
- 11284
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UniProt
- Q96T60
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途径
- DNA Damage Repair, Nucleotide Phosphorylation
抗原
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