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PTRF 抗体 (AA 47-390) (HRP)

The HRP-conjugated 兔 多克隆 anti-PTRF antibody (ABIN8024359) specifically detects PTRF in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8024359
发货至: 中国
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Quick Overview for PTRF 抗体 (AA 47-390) (HRP) (ABIN8024359)

抗原

See all PTRF 抗体
PTRF (Polymerase I and Transcript Release Factor (PTRF))

适用

  • 52
  • 28
  • 25
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 5

克隆类型

  • 49
  • 3
多克隆

标记

  • 33
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PTRF antibody is conjugated to HRP

应用范围

  • 29
  • 16
  • 13
  • 10
  • 6
  • 6
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 47-390

    原理

    Anti-PTRF/CAVIN1 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PTRF/CAVIN1 recombinant protein (Position: D47-D390).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PTRF (Polymerase I and Transcript Release Factor (PTRF))

    别名

    CAVIN1

    背景

    Background: This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.

    Gene Full Name: caveolae associated protein 1

    基因ID

    284119

    UniProt

    Q6NZI2
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