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PARN 抗体 (AA 1-301) (Fluoro647)

This 兔 多克隆 antibody specifically detects PARN in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8023907
发货至: 中国
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Quick Overview for PARN 抗体 (AA 1-301) (Fluoro647) (ABIN8023907)

抗原

See all PARN 抗体
PARN (Poly A Specific Ribonuclease (PARN))

适用

  • 64
  • 33
  • 30
  • 14
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 43
  • 21

克隆类型

  • 46
  • 18
多克隆

标记

  • 33
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PARN antibody is conjugated to Fluoro647

应用范围

  • 38
  • 20
  • 20
  • 18
  • 13
  • 6
  • 6
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 23
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-301

    原理

    Anti-PARN Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human PARN recombinant protein (Position: M1-Y301).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PARN (Poly A Specific Ribonuclease (PARN))

    别名

    PARN

    背景

    Background: Poly (A)-specific ribonuclease (PARN), also known as polyadenylate-specific ribonuclease or deadenylating nuclease (DAN), is an enzyme that in humans is encoded by the PARN gene. The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly (A) as the substrate, hence, efficiently degrades poly (A) tails of mRNAs. Exonucleolytic degradation of the poly (A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons.

    Gene Full Name: poly(A)-specific ribonuclease

    基因ID

    5073

    UniProt

    O95453
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