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PLAUR 抗体 (C-Term) (FITC)

The FITC-conjugated 兔 多克隆 anti-PLAUR antibody (ABIN8022961) specifically detects PLAUR in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8022961
发货至: 中国
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Quick Overview for PLAUR 抗体 (C-Term) (FITC) (ABIN8022961)

抗原

See all PLAUR 抗体
PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

适用

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宿主

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克隆类型

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多克隆

标记

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This PLAUR antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-uPA Receptor/PLAUR Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human uPA Receptor.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

    别名

    PLAUR

    背景

    Background: PLAUR (PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.

    Gene Full Name: plasminogen activator, urokinase receptor

    Sequence Similarities: Contains 3 UPAR/Ly6 domains.

    基因ID

    5329

    UniProt

    Q03405

    途径

    Inositol Metabolic Process
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