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PLAUR 抗体 (AA 25-261)

The 兔 多克隆 anti-PLAUR antibody is suitable to detect PLAUR in samples from 大鼠 和 小鼠. It has been validated for WB, IHC, ELISA 和 FACS.
产品编号 ABIN8022933
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PLAUR 抗体 (AA 25-261) (ABIN8022933)

抗原

See all PLAUR 抗体
PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

适用

  • 141
  • 70
  • 63
大鼠, 小鼠

宿主

  • 126
  • 31
  • 6
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  • 3

克隆类型

  • 135
  • 37
多克隆

标记

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This PLAUR antibody is un-conjugated

应用范围

  • 82
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

质量等级

Carrier-free
  • 抗原表位

    • 23
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    AA 25-261

    原理

    Anti-uPA Receptor/Plaur Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-uPA Receptor/Plaur Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived rat uPA Receptor recombinant protein (Position: L25-R261).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Rat ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

    别名

    Plaur

    背景

    Background: PLAUR (PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.

    Gene Full Name: plasminogen activator, urokinase receptor

    分子量

    50 kDa

    基因ID

    50692

    UniProt

    P49616

    途径

    Inositol Metabolic Process
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