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PLAT 抗体 (C-Term) (Fluoro488)

The Fluoro488-conjugated 兔 多克隆 anti-PLAT antibody (ABIN8022892) specifically detects PLAT in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8022892
发货至: 中国
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Quick Overview for PLAT 抗体 (C-Term) (Fluoro488) (ABIN8022892)

抗原

See all PLAT 抗体
PLAT (Plasminogen Activator, Tissue (PLAT))

适用

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人, 小鼠, 大鼠

宿主

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  • 1
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克隆类型

  • 136
  • 36
多克隆

标记

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This PLAT antibody is conjugated to Fluoro488

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-TPA Tissue Plasminogen Activator/PLAT Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human PLAT, which shares 87.5% and 79.2% amino acid (aa) sequence identity with mouse and rat PLAT, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PLAT (Plasminogen Activator, Tissue (PLAT))

    别名

    PLAT

    背景

    Background: PLAT is also known as tPA. This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

    Gene Full Name: plasminogen activator, tissue type

    基因ID

    5327

    UniProt

    P00750

    途径

    Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
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