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PLAT 抗体 (AA 366-562) (HRP)

The 兔 多克隆 anti-PLAT antibody is suitable to detect PLAT in samples from 人. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN8022885
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PLAT 抗体 (AA 366-562) (HRP) (ABIN8022885)

抗原

See all PLAT 抗体
PLAT (Plasminogen Activator, Tissue (PLAT))

适用

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宿主

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克隆类型

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多克隆

标记

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This PLAT antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    AA 366-562

    原理

    Anti-TPA Tissue Plasminogen Activator/PLAT Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human TPA shares 83%,84% amino acid (aa) sequence identity with mouse,rat TPA,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TPA recombinant protein (Position: H366-P562). Human TPA shares 83% and 84% amino acid (aa) sequence identity with mouse and rat TPA, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PLAT (Plasminogen Activator, Tissue (PLAT))

    别名

    PLAT

    背景

    Background: PLAT is also known as tPA. This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

    Gene Full Name: plasminogen activator, tissue type

    Sequence Similarities: Belongs to the peptidase S1 family.

    基因ID

    5327

    UniProt

    P00750

    途径

    Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
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