IRGM 抗体 (AA 51-150) (Cy5.5)
Quick Overview for IRGM 抗体 (AA 51-150) (Cy5.5) (ABIN752568)
抗原
See all IRGM 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 51-150
-
预测反应
- Human,Mouse,Rat,Dog
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human IRGM
-
亚型
- IgG
-
-
anti-Immunity-Related GTPase Family, M (IRGM) (AA 151-179), (C-Term) antibody
IRGM 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB20841 unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- IRGM (Immunity-Related GTPase Family, M (IRGM))
-
别名
- IRGM
-
背景
-
Synonyms: Irgm, I1, Iigp3, Immunity related GTPase family M protein 1, Immunity related GTPase family, M, Interferon inducible protein 1, IRGM1, LRG 47, LRG47, IRGM_HUMAN.
Background: IRGM belongs to a family of interferon-gamma inducible GTPases, belonging to the GTPase superfamily, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation. IRGM is primarily expressed in all cells derived from B-cell lineages, and is highly expressed in macrophages following IFN-gamma stimulation. IRGM has been shown to be required for host defences against a broad range of intracellular pathogens. Specifically, IRGM deficient mice show defects with intracellular microbial killing, phagosome maturation and autophagy. More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli.
-
基因ID
- 345611
抗原
-
