PLCE1 抗体 (AA 4-735) (Biotin)
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北京 101111
Quick Overview for PLCE1 抗体 (AA 4-735) (Biotin) (ABIN8022169)
抗原
See all PLCE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-735
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原理
- Anti-PLCE1 Antibody Biotin Conjugated
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预测反应
- Human PLCE1 shares 74.6%,73.6% amino acid (aa) sequence identity with mouse,rat PLCE1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PLCE1 recombinant protein (Position: E4-E735). Human PLCE1 shares 74.6% and 73.6% amino acid (aa) sequence identity with mouse and rat PLCE1, respectively.
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亚型
- IgG
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anti-Phospholipase C, epsilon 1 (PLCE1) (AA 1-250) antibody
PLCE1 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, epsilon 1 (PLCE1) (AA 1-250) antibodyPLCE1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, epsilon 1 (PLCE1) antibodyPLCE1 适用: 人, 小鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, epsilon 1 (PLCE1) (AA 4-735) antibodyPLCE1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- PLCE1 (Phospholipase C, epsilon 1 (PLCE1))
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别名
- PLCE1
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背景
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Background: Phospholipase C epsilon 1 (PLCE1) is an enzyme that in humans is encoded by the PLCE1 gene. This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These second messengers subsequently regulate various processes affecting cell growth, differentiation, and gene expression. This enzyme is regulated by small monomeric GTPases of the Ras and Rho families and by heterotrimeric G proteins. In addition to its phospholipase C catalytic activity, this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity. Mutations in this gene cause early-onset nephrotic syndrome, characterized by proteinuria, edema, and diffuse mesangial sclerosis or focal and segmental glomerulosclerosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Full Name: phospholipase C epsilon 1
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基因ID
- 51196
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UniProt
- Q9P212
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途径
- EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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